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Xiangsen Chen on Muck Rack

Xiangsen Chen

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Articles

Modulation of the gut–liver axis via TMAO metabolism by Ramulus Mori alkaloids alleviates diabetic atherosclerosis

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By Tingting Wang, Han Liu, Shan Chen, Yanmin Chen, Yuanyuan Liu, Zhihua Liu, Weilian Bao, Jun Ye, Yuling Liu, Xiangsen Chen
| Nature Verified
Abstract Diabetic atherosclerosis is a complex condition driven by intertwined metabolic disturbances including hyperglycemia, dyslipidemia, inflammation, and oxidative stress. The gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) has emerged as a key contributor that links metabolic disorders to vascular injury.
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