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Xianshan Hu on Muck Rack

Xianshan Hu

As seen in: Frontiers in Immunology
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Articles

Multidimensional neuropsychological heterogeneity in obstructive sleep apnea: deep clinical phenotyping in a single-center cohort, population proteomic context, and depressive-burden risk stratification

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By Xiaoyu Wang, Yirun Jiang, Leilei Yu, Pengfei Ye, Chutian Xing, Wen Hu, Zhi Qiao, Shizhen Zou, Siyuan Hou, Rui Zhang, Jinrang Li, Jun Tai, Xianshan Hu
| Frontiers in Immunology
Abstract Background: Obstructive sleep apnea (OSA) is associated with substantial cognitive and affective burden, yet conventional respiratory severity does not fully explain this heterogeneity. We investigated whether neuropsychological vulnerability in OSA shows differentiated clinical association patterns, whether cognition, depression, and anxiety share general-population proteomic associations, and whether a separate depressive-burden model can support pragmatic risk stratification.
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