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Xianying Zhou on Muck Rack

Xianying Zhou

As seen in: Frontiers in Immunology, Royal Society of Chemistry
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Articles

Deciphering fibroblast and myeloid-cell states in keloids: an integrative analysis identifies ANKRD1 as a ferroptosis-related candidate gene

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By Rongrong Xie, Wanting Yao, Peipei Chen, Xianying Zhou, Xinyu Jia, Yuyang Lin, Zehao Yu, Shijie Tang, Caixiang Chen, Chaoyang Wang, Xingong Lin, Penghong Chen
| Frontiers in Immunology
Abstract Background: Keloids are fibroproliferative skin disorders characterized by persistent extracellular matrix deposition and limited treatment options. Ferroptosis has been implicated in fibrosis, but the molecular basis of ferroptosis-related changes in keloids remains unclear. Methods: Fibroblast-derived bulk transcriptomic datasets (GSE44270 and GSE145725) were integrated to identify differentially expressed ferroptosis-related genes.
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Visible-light induced acridinium-catalyzed selective N-dealkylation of N-heterocycles

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By Shanshan Liu, Yaoyao Zhang, Lin-Yu Jiao, Xianying Zhou
| Royal Society of Chemistry Verified
Visible-light induced acridinium-catalyzed selective N-dealkylation of N-heterocycles We have developed an efficient and general strategy for N-chlorosuccinimide (NCS) promoted N-dealkylation of aza-heterocycles via acridinium photocatalyzed electron transfer and hydrogen atom transfer. This approach effectively obviates the need for transition-metal catalysis and is highlighted by wide substrate scope as well as exclusive chemo-selectivities.
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