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Xiao-Ding Liu

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Articles

3D genomic mapping reveals multifocality of human pancreatic precancers - Nature

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By Alicia Braxton, Ashley L. Kiemen, Mia P. Grahn, Jeeun Parksong, Jiaying Lai, Lily Zheng, Stephanie Mou, Xiao-Ding Liu, Niklas Bachmann, YunZhou Liu, Jocelyn Hsu, Linda Chu, Elliot Fishman, Nicholas Roberts, Robert B. Scharpf, Toby Cornish, Yuchen Jiao, Rachel Karchin, Ralph H. Hruban, Pei-Hsun Wu, Denis Wirtz
| Nature Verified
Abstract Pancreatic intraepithelial neoplasias (PanINs) are the most common precursors of pancreatic cancer, but their small size and inaccessibility in humans make them challenging to study1. Critically, the number, dimensions and connectivity of human PanINs remain largely unknown, precluding important insights into early cancer development.
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