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Articles by Xiaofei Zhang
Effects of seven traditional Chinese sports on physiological outcomes in individuals receiving treatment for substance use disorder: a network meta-analysis of randomized controlled trials
Abstract Background Substance use disorder is a major public health challenge, with physiological consequences, including dysregulated blood pressure, abnormal heart rate, and altered body composition, which increase the risk of cardiovascular disease and mortality. Physical exercise shows rehabilitation potential, but evidence-based guidance on optimal traditional Chinese exercise regimens is lacking.
Muscle fiber types in mutton: implications for meat quality and flavor formation—a review
Abstract Mutton quality and flavor are closely associated with muscle fiber type composition. This review summarizes muscle fiber classification, mutton flavor formation pathways, and the effects of muscle fiber types on color, pH, tenderness, juiciness, and flavor compounds. It also discusses how genotype, age, sex, feeding practices, and nutrition regulate mutton quality through muscle fiber transformation, providing references for high-quality mutton production.
TRIM21-dependent ubiquitination of MCCase induced by hsa_circ_0009061 drives H3K36 crotonylation to suppress epithelial ovarian cancer progression through regulating glycolysis
Abstract Histone lysine crotonylation plays a pivotal role in gene transcription in diseases. However, the relationship between its levels and epithelial ovarian cancer (EOC) peritoneal metastasis remains unclear. Here, we report that the circular RNA hsa_circ_0009061 is crucial for 3-Methylcrotonyl-CoA carboxylase (MCCase)-mediated lysine crotonylation and glycolysis. Hsa_circ_0009061 acts as a tumor suppressor and inhibits EOC metastasis as well as glycolysis.
Novel adaptive fixed-time synchronization for fractional-order uncertain Hopfield neural networks with proportional delays of unbounded nature
Abstract The fixed-time synchronization of fractional-order uncertain Hopfield neural networks (FOUHNNs) with proportional delays is investigated in this paper. Proportional delays, unlike constant or bounded variable delays, are time-varying and unbounded, thereby posing challenges to the synchronization control of fractional master-slave systems.
A novel bispecific antibody targeting Frizzled7/PD-L1 overcomes NSCLC resistance to atezolizumab by reprogramming tumor microenvironment
Abstract Immunotherapy efficacy in non-small cell lung cancer (NSCLC) remains limited, and aberrant activation of the Wnt/β‑Catenin pathway plays a significant role. However, the precise involvement of its receptor, Frizzled7 (Fzd7), in immune checkpoint inhibitor (ICI)-resistance remains unexplored.
Study on the construction of a model for particle size distribution of coal fines in the full wellbore of coalbed methane wells
Abstract During the drainage process of coalbed methane wells in the Panhe Block of the Qinshui Basin, severe coal fines production restricts productivity release. This study aims to systematically elucidate the vertical distribution patterns of coal fines particle sizes within the wellbore, providing a basis for quantitative optimization of drainage systems.
Reversible Exfoliation-Aggregation Dynamics in Ionic COFs for Tunable Interfacial Catalysis
1 Introduction Heterogeneous functional materials are among the most widely utilized platforms in catalysis, adsorption, and mass transfer, offering advantages such as high selectivity, extended lifetime, tunable structures, robust stability, environmental tolerance, and potential for recyclability [1-7]. These materials are also compatible with diverse energy input modalities, including light, electricity, and heat [8-17].
The association between obstructive sleep apnea and total cerebral small vessel disease burden—Neurovascular insights of OSA
Abstract Objective: This study was conducted to assess the relationship between the severity of obstructive sleep apnea (OSA) and the total burden score of cerebral small vessel disease (CSVD), global cerebral blood flow (CBF), and cognitive function. Moreover, the internal pathway through which OSA induces cognitive impairment by affecting cerebral perfusion, and overall cerebral small vessel lesions was determined in this study.
Author Correction: HERD-1 mediates multiphase condensate immiscibility to regulate small RNA-driven transgenerational epigenetic inheritance
Correction to: Nature Cell Biology https://doi.org/10.1038/s41556-024-01514-8, published online 1 October 2024. In the version of this article initially published, in Extended Data Fig. 5, the WT / gfp RNAi panel was an inadvertent duplicate of the adjacent hrde-1(ths685) panel; in Extended Data Fig. 6c and associated Source Data, replicate 3 of herd-1(-) was inadvertently duplicated from replicate 2 during data preparation. In Fig.
The Influence of Buying vs. Receiving an IT-based Device on User Commitment
gift giving, human-IT interaction, emotional support, cognitive value, device commitment Zhang, X., Valacich, J.S., Jenkins, J.L., Guo, X., (2018) "The Influence of Buying vs. Receiving an IT-based Device on User Commitment" Proceedings of the Seventeenth Annual Workshop on HCI Research in MIS, San Francisco, California, USA, December 13. Zhang, Xiaofei; Valacich, Joseph S.; Jenkins, Jeffrey L.; and Guo, Xitong, "The Influence of Buying vs. Receiving an IT-based Device on User Commitment" (2018).
Estimating Xisha watermelon yield using sampling and global scanning based on drone remote sensing
[1] Adesipo A, Fadeyi O, Kuca K, Krejcar O, Maresova P, Selamat A, et al. Smart and climate-smart agricultural trends as core aspects of smart village functions. Sensors, 2020; 20（21）: 5977. [2] Maddikunta P K R, Hakak S, Alazab M, Bhattacharya S, Gadekallu T R, Khan W Z, et al. Unmanned aerial vehicles in smart agriculture: Applications, requirements, and challenges. Sensors, 2021; 21（16）: 17608–17619. [3] Gatkal N R, Nalawade S M, Shelke M S, Sahni R K, Walunj A A, Kadam P B, et al.
Mechanism and application of Taq DNA polymerase in TaqMan qPCR
Abstract TaqMan quantitative real-time PCR (qPCR) is widely used in molecular biology due to its high specificity, sensitivity, and multiplexing capability. Taq DNA polymerase (Taq pol) plays a central role by simultaneously catalyzing DNA synthesis and cleaving fluorogenic probes, yet the mechanistic interplay between these activities remains incompletely characterized. We systematically quantified Taq pol nuclease and polymerase activities during extension and probe cleavage.
Shared subcortical–default mode morphological dysconnectivity in adolescent bipolar disorder, major depressive disorder and schizophrenia
Abstract Adolescence is a critical window of vulnerability to psychiatric disorders, yet transdiagnostic network abnormalities remain poorly characterized at this stage. Here, we compare single-subject morphological brain networks in 61 adolescents with bipolar disorder (BD), 73 with major depressive disorder (MDD), 55 with schizophrenia (SCH), and 181 healthy controls.
A framework for the exploration of subcellular compartmentalization of RNA-binding proteins
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Abstract The ability of RNA-binding proteins to form complexes with other biomolecules underpins a broad range of structural properties and functions. Understanding the subcellular distribution of RNA-binding proteins and their interacting partners in the steady state and upon perturbation can therefore shed light on these aspects.
By Xiangpeng Guo, Jieyi Hu, Muqddas Tariq, Jingxia Zheng, Mingwei Sun, Yuanyuan Lu, Jingjing Wang, Aiping Wang, Álvaro Castells-García, Xiyuan Zheng, Bin Peng, Dongye Wang, Xiaofeng Wei, Tao Yang, Giacomo Volpe, Liang Wu, Abdul Mazid, Wenjuan Li, Yiwei Lai, Dajiang Qin, Francesca Aguilo, Yu Zhou, Chuanyu Liu, Maria Pia Cosma, Xingzhi Xu, Emma Lundberg, Jan Mulder, Andrew Hutchins, Patrick H Maxwell, Luciano Di Croce, Xiaofei Zhang, Miguel Esteban, Yuan Lv, Shahzina Kanwal, Jianwen Yuan, Mengling Jiang
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Nature
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Patch-to-slide fusion deep learning model for histological diagnosis of early pregnancy loss including hydatidiform mole
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Abstract Distinguishing histological subtypes of early pregnancy loss is crucial for clinical practice. Current gold standards combining pathological and molecular profiling are costly, limiting implementation. We developed a patch-to-slide fusion artificial intelligence (AI) model with adaptive masking to predict histological diagnosis.
By Yating Zhao, Xinhui He, Xin Tao Ye, Zhe Wang, Bo Huang, Jiaqi Ning, Limeng Cai, Peilin Han, Huifang Zhang, Hao Chen, Xiangang Yin, Jie Dong, Ping Duan, Huafeng Shou, Kai Yan, Min Hu, Ruiqi Sun, Qihong Wan, Qiwei Zheng, Wanting Huang, Haixia Luo, Jue Xie, Xiaofei Zhang, Xiang Rong Tian, Jianhua Qian, Qingmei Han, Xiupu Liu
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Nature
Verified
Author Correction: A feedback regulatory loop by MAPK–CCA1 engages auxin signalling to stimulate root foraging for nitrate
Correction to: Nature Plants https://doi.org/10.1038/s41477-026-02225-8, published online 12 February 2026. In the version of this article initially published, two relevant references were unintentionally overlooked and have now been included. The reference “Regnard, S. et al. The MKK3 module integrates nitrate and light signals to modulate secondary dormancy in Arabidopsis thaliana. Proc. Natl. Acad. Sci.
Cryo-EM structure of a photosystem I supercomplex from Euglena gracilis containing pentameric LHCE and dimeric LHCII
Abstract Euglenophyta is a representative phylum of green-lineage secondary endosymbiotic eukaryotes. These organisms have evolved far-red light-harvesting complexes (LHCs) composed of diadinoxanthin and chlorophyll a/b, which are now classified as the LHCE family. Here we report a 2.35-Å cryo-electron microscopy structure of photosystem I (PSI) supercomplex from Euglena gracilis, with all subunits and their paralogs assigned.
A pipeline leakage detection method for boiler energy operation system using enhanced SVM-based acoustic emission technology - Scientific Reports
Abstract Pipeline leakage detection in boiler energy systems is essential for operational safety and efficiency, yet conventional techniques such as pressure-based and mass-balance methods often lack real-time performance and sensitivity to small leaks. Although acoustic emission (AE) technology offers dynamic, non-destructive monitoring, its practical application is hindered by noise interference and limited training samples under industrial conditions.
Deep learning-based suppression of cold reflections in infrared systems
This study proposes a deep learning-based method to suppress cold reflection artifacts in cooled mid-wave infrared imaging systems. First, a mid-wave infrared optical system is designed, followed by a cold reflection simulation using the Narcissus macro. Second, an equivalent temperature difference superposition method is adopted to generate synthetic infrared images with cold reflection patterns, thereby establishing a multi-scene dataset.
A feedback regulatory loop by MAPK–CCA1 engages auxin signalling to stimulate root foraging for nitrate - Nature Plants
Abstract In eucaryotes, mitogen-activated protein kinase (MAPK) cascades are evolutionarily conserved signalling modules crucial for growth regulation and stress tolerance. However, the regulatory role of MAPK in nutrient sensing by plants remains largely unclear. Here we uncovered MEKK14 and its paralogue MEKK13 determine lateral root elongation via enhanced cell division and expansion.
Editorial: Digital information for patient education, volume II
1 Introduction Recent advances in digital technologies—such as online platforms, big data, live streaming, and artificial intelligence (AI)—are transforming how health and medical information is generated, shared, and managed, giving rise to new models of medical information management (1–3). Through digital health information systems, patients can access medical knowledge remotely, which has been shown to improve their wellbeing (4, 5).
Neoadjuvant Therapy‐Induced Remodeling in Pancreatic Ductal Adenocarcinoma: Multimodal Spatial Analysis and Prognosis
CAF cancer-associated fibroblast CPA collagen proportion area DDR DNA damage response EC enrichment coefficient FDR false discovery rate HR hazard ratio NAT neoadjuvant therapy PDAC pancreatic ductal adenocarcinoma TAN tumor associated neutrophil TLS tertiary lymphoid structure TME tumor microenvironment TPA tumor proportion area Treg regulatory T cell TRG tumor regression grading 1 Introduction Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate of only 13% [1, 2].
Un modelo híbrido de voz y texto detecta depresión en adolescentes con alta precisión
Me Gusta 2 2 Comentar 2 2 Autor/autores: Chenxi Wang, Xiaofei Zhang , Jiaqi Sun...(et.al) Fecha de publicación: 09/01/2026 Artículo | CONTENIDO PUB GENERAL+PSICÓLOGOS | Artículo revisado por nuestra redacción La depresión mayor en adolescentes (MDD) se ha convertido en un importante problema de salud pública, con un aumento sostenido de su prevalencia durante la última década y un fuerte impacto en el funcionamiento social, académico y futuro laboral de los jóvenes.
Genetic characteristics of influenza A/H3N2 virus in Jiaxing, China (2019–2024) - Virology Journal
Between January 1, 2019, and December 31, 2024, 7,872 ILI samples were collected from designated hospitals in Jiaxing, and influenza A/H3N2 virus was detected in these samples. Among these samples, 636 influenza A/H3N2 viruses were identified, and six epidemic peaks were observed from 2019 to 2024. Out of the six epidemic peaks, two were observed in 2019, two in 2022, and two in 2023 (Fig. 1A).
Vacancy‐Engineered Ceria Enables 4f‐Orbital‐Driven Redox Catalysis for Bidirectional Sulfur Conversion in Li─S Batteries
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma71260-sup-0001-SuppMat.docx13.9 MB Supporting Information References 1, , , , , , , , , , , , , , , , Nature 2024, 626, 98. 2, , , , , Chem. Rev. 2024, 124, 4935. 3, , , , , , , , , , , , , Energy Environ. Sci. 2024, 17, 1330. 4, , , , , , , , , Chem. Soc. Rev. 2025, 54, 4822. 5, , , , , , , , Adv. Mater. 2025, 37, 2419089. 6, , , , , , , , , , Nano-Micro Lett. 2024, 16, 12. 7, , , , , , , , , Adv.
Nickel‐Mediated Synthesis of Fused Heterocycle‐Linked Covalent Organic Frameworks for Self‐Sensitized Photocatalysis
Conflict of Interests The authors declare no conflict of interest. Supporting Information Filename Description anie70090-sup-0001-SuppMat.pdf4 MB Supporting Information References 1, , Chem. Soc. Rev. 2021, 50, 1813–1845, https://doi.org/10.1039/D0CS00793E. 2, , , , , , , , , , , , , , , Nature 2024, 635, 96–101, https://doi.org/10.1038/s41586-024-08080-x. 3, , , , , , , , , , , , Matter 2024, 7, 1406–1439. 4, , , , , , , , , , , , , , , Angew. Chem. Int. Ed. 2023, 62, e202310937. 5, , , Angew. Chem. Int.
Rapid and sensitive acute leukemia classification and diagnosis platform using deep learning-assisted SERS detection
Keywords surface enhanced raman scattering acute leukemia deep learning cerebrospinal fluids Introduction Central nervous system leukemia (CNSL) is the main cause of leukemia relapse and drug resistance development and potentially results in serious complications and life-threatening situations. Rapid identification and immediate symptomatic treatment are of paramount importance for patients with CNSL.1,2 Most CNSL patients have no symptoms or atypical symptoms in the early stage.
An adversarial gradual domain adaptation approach for fault diagnosis via intermediate domain generation
Advanced search Nondestructive Testing and Evaluation Latest Articles Submit an article Journal homepage Full Article Figures & data References Citations Metrics Reprints & Permissions Read this article /doi/full/10.1080/10589759.2025.2545553?needAccess=true ABSTRACT Intelligent fault diagnosis technology, as a fundamental aspect of modern Nondestructive Testing and Evaluation (NDT&E), is critical for ensuring the safe operation of electrical equipment.
Design and experiment of the negative pressure adsorption Cartesian robot system for apple harvesting
Xiaofei Zhang, Yi Xun, Qinghua Yang, Zhiheng Wang Keywords harvesting robot, apple, negative pressure adsorption, field trial Full Text: PDF References Cheng J L, Guo W C, Zhang Z Y, Zeng S C, Wang Z W. Optical properties of ‘Gala’（Malus pumila） apple pulp and their relationship with internal quality. Infrared Physics & Technology, 2022; 123: 104210. DOI: 10.1016/j.infrared.2022.104210 Zhao X, Cao G H, Zhang P F, Ma Z H, Zhao L J, Chen J N.
In Situ Detection and Measurement of Broccoli Heads Under Different Lighting Conditions Using Proximal Remote Sensing
Conflicts of Interest The authors declare no conflicts of interest. References , , and . 2016. “Machine Vision for a Selective Broccoli Harvesting Robot.” IFAC-PapersOnLine 49, no. 16: 66–71. https://doi.org/10.1016/J.IFACOL.2016.10.013. , , , , and . 2021. “The Effect of Data Augmentation and Network Simplification on the Image-Based Detection of Broccoli Heads With Mask R-CNN.” Journal of Field Robotics 38, no. 1: 85–104. https://doi.org/10.1002/rob.21975. , , , and . 2021.
3D Printing of Self-powered Piezoelectric Sensor Enabled Gait Recognition via Deep Learning Wearable gait analysis systems leveraging piezoelectric sensing and artificial intelligence hold significant potential for non-invasive monitoring of neurodegenerative disorders. However, challenges remain in current gait analysis due to the high computational costs, the algorithmic complexity, and data privacy constraints.
A High-Temperature Stabilized Anti-Interference Beidou Array Antenna
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Research trends and hotspots of gut microbiota and its metabolites in | JMDH
Kaixuan Zhang,1 Yajun Shi,1 Lirong Peng,2 Xiaofei Zhang,1 Nanbo Zheng,2 Jiajing Xin,1 Junbo Zou,1 Fei Luan1,2 1Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xi’an, 712046, People’s Republic of China; 2Department of Pharmacy, Xi’an Central Hospital, Xi’an, Shaanxi, 710000, People’s Republic of China Correspondence: Junbo Zou, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine...
Morphology evolution and formation mechanism of wrinkled Cr films on liquid surfaces
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Research on the Mechanism and Dynamic Characteristics of Intermittent Failure of Electrical Connectors
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Libing Ren 1,*, Xiaofei Zhang 1 and Xuke Lan 2 1 College of Electrical and Information Engineering, Hunan University, Changsha 410082, China 2 Beijing Institute of Technology Chongqing Innovation Center, Chongqing 401120, China * Author to whom correspondence should be addressed. Appl. Sci.
Study on the removal of Cr(vi) from ethylene wastewater using stabilized nanoscale zero-valent iron based on porous basalt material In this research, the authors prepared stabilized nanoscale zero-valent iron based on natural basalt material and used it to remove Cr(VI) from ethylene wastewater. SEM, TEM, FTIR, XRD, BET and other means were used to characterize the material (BM-nZVI-CMC) before and after loading.
Dual Radar: A Multi-modal Dataset with Dual 4D Radar for Autononous Driving - Scientific Data
Abstract 4D radar has higher point cloud density and precise vertical resolution than conventional 3D radar, making it promising for adverse scenarios in the environmental perception of autonomous driving. However, 4D radar is more noisy than LiDAR and requires different filtering strategies that affect the point cloud density and noise level.
Two-Dimensional DOA Estimation for Coprime Planar Arrays: From Array Structure Design to Dimensionality-Reduction Root MUSIC Algorithm
1. Introduction Sensor array signal processing is a crucial field within modern signal processing, involving the arrangement of multiple sensors at different spatial positions to form a coherent array. This configuration enables the reception and analysis of spatial signals by sampling distributed field data and converting them into discrete spatial observations.
Molecular Mechanisms of Gene Expression Regulation in Response to Heat Stress in Hemerocallis fulva
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Tetraploidization Altered Phenotypic Traits and Metabolite Profile of Java Ginseng (Talinum paniculatum (Jacq.) Gaertn.)
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Covalent Organic Frameworks with Carbon‐Centered Radical Sites for Promoting the 4e− Oxygen Reduction Reaction
Conflict of Interests The authors declare no conflict of interest. Supporting Information As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors.
Analysis of Subtype, Molecular Clusters and Drug Resistance in Newly Diagnosed Individuals with HIV-1 Infection in Jiaxing City, Zhejiang Province, China in 2023
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DEAD-box RNA helicase 10 is required for 18S rRNA maturation by controlling the release of U3 snoRNA from pre-rRNA in embryonic stem cells - Nature Communications
Abstract Ribosome biogenesis plays a pivotal role in maintaining stem cell homeostasis, yet the precise regulatory mechanisms governing this process in mouse embryonic stem cells (mESCs) remain largely unknown.
Unraveling the Anthocyanin Regulatory Mechanisms of White Mutation in Verbena stricta by Integrative Transcriptome and Metabolome Analysis
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Impact of Paroxysmal Atrial Tachycardia on Thromboembolic Events and Major Adverse Cardiovascular Events: A Single-Center Retrospective Study
Abstract Objective Atrial fibrillation (AF) is known to increase the risk of thromboembolic events and major adverse cardiovascular events (MACE). The impact of paroxysmal atrial tachycardia (PAT) on these risks remains unclear. Methods This retrospective cohort study was conducted involving 889 patients diagnosed with PAT and 1106 control patients without PAT, all of whom underwent their initial 24-hour ECG monitoring between 2015 to 2020.
Quantitative Study of Thermal Response of Timber-Concrete Composite Structures Under Traveling Fire Using Energy Equivalence Method
Conflicts of Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. References 1 CEN, EN 1991-1-2 Eurocode 1: Actions on Structures - Part 1–2: General Actions on Structures Exposed to Fire (Brussels: European committee for standardization, 2002).
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