Xiaoguo Zhai on Muck Rack

Xiaoguo Zhai

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Articles

Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains - Nature Communications

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By Xiaolong Li, Shuansuo Wang, Yanfeng Wang, Honggang Hu, Jiawei Wang, Feng Wang, Lining Lu, Xiaoguo Zhai, Lujun Liang, Xiangdong Fu, Ziqing Mei
| Nature Verified
Abstract Linear (Met1-linked) ubiquitination is involved inflammatory and innate immune signaling. Previous studies have characterized enzymes regulating the addition and removal of this modification in mammalian systems. However, only a few plant-derived deubiquitinases targeting Met1-linked ubiquitin chains have been reported and their mechanism of action remains elusive.
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