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Xiaoling Yin

As seen in: Nature, Wiley Online Library, MDPI
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Articles

Single-cell and deep learning identify hypoxia-responsive lncRNAs predicting outcomes in colorectal cancer

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By Susu Han, Xiaoling Yin, Yufei Tang, Wang Yao, Tingting Zhu, Shi Qi, Xiaomei Xie, Tao Huang, Fenggang Hou
| Nature Verified
Abstract Emerging evidence highlights hypoxia-responsive long non-coding RNAs (lncRNAs) as potential modulators in tumor biology. In this study, we explored the significance of a hypoxia-responsive lncRNA molecular signature (HRLPMS) and the therapeutic implications of hypoxia-responsive lncRNAs in colorectal cancer (CRC).
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East Meets West in Allergic Airway Disease: Insights From the EAACI Hong Kong Allergy School 2025

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By Xiaoling Yin, Juan Meng, Stephen R. Durham, Stefano Del Giacco
| Wiley Online Library Verified
Allergic airway diseases, including allergic rhinitis and asthma, constitute a significant global health concern, affecting nearly one-third of the world's population and incurring substantial social, economic, and healthcare burdens [1]. These conditions often coexist as a “united airway” disease, underscoring the need for multidisciplinary and integrated management strategies.
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Insights into the formulation of lipid nanoparticles for the optimization of mRNA therapeutics

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By Xiangyu Jiao, Sichuan Chengdu, Shugang Qin, Xiaoling Yin
| Wiley Online Library Verified
mRNA-based therapeutics increasingly demonstrate significant potential in treating various diseases, including infectious diseases, cancers, and genetic disorders. Effective delivery systems are crucial for advancing mRNA therapeutics. Lipid nanoparticles (LNPs) serve as an excellent carrier, widely validated for their safety and tolerability in commercially available mRNA vaccines.
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