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Articles by Xiaoping Yan
Sex-associated patterns of disease activity and physical function in ankylosing spondylitis: real-world cross-sectional evidence
Abstract Objective: To characterize sex-associated differences in disease activity and physical function in ankylosing spondylitis (AS) and to formally test whether the cross-sectional BASFI–ASDAS association differed by sex. Methods: We conducted a real-world cross-sectional analysis of 530 Chinese outpatients with rheumatologist-documented AS (387 men and 143 women).
PBPK modeling predicts rilzabrutinib dose adjustments using BTK occupancy for CYP3A4 interactions and hepatic impairment
Abstract This study aimed to develop and validate a population-based physiologically-based pharmacokinetic (PBPK) model for the Bruton’s tyrosine kinase inhibitor rilzabrutinib (RIL) to predict its pharmacokinetic (PK) and BTK occupancy (BO) profiles under various scenarios, including drug-drug interactions (DDIs) with CYP3A4 modulators and in patients with hepatic impairment. A PBPK model for RIL was constructed using PK data, BO parameters, and interaction parameters.
Simulation Research on the Dual-Electrode Current Excitation Method for Distance Measurements While Drilling
1. Introduction Complex structure well drilling technology has been widely applied in oil and gas well exploration, such as with horizontal wells, cluster wells, and relief wells. During the operation process, encountering issues related to multi-well collision prevention, obstacle avoidance, and interconnections is inevitable.
Sodium Alginate-Montmorillonite Composite Film Coatings for Strawberry Preservation
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Remote Sulfonylation of Anilines with Sodium Sulfifinates Using Biomass-Derived Copper Catalyst
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
An International Nursing Student’s Journey to Culturally Safe Nursing Care
Nursing Philosophy Statement: Nurses are responsible and accountable to provide person-centred and culturally safe care. As frontline healthcare providers, advocators and educators, nurses support patients, families and communities, promoting physical, emotional, social and cultural wellbeing.
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