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Comment on: Substitution Patterns After Discontinuation of CNS-Active Medications in Older Adults in Primary Care
To the Editor, We read with interest the Brief Report by Gray et al., which used STOP-FALLS data to describe medication substitutions after discontinuation of central nervous system (CNS)-active medications in older adults in primary care [1]. The authors address an underexamined question in deprescribing research: whether discontinuing a high-risk medication reduces overall medication-related risk or is followed by risk-preserving substitution.
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