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Xiaoye Ran on Muck Rack

Xiaoye Ran

As seen in: Frontiers
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Articles

An engineered and scalable human cell-derived extracellular matrix demonstrates advantages over recombinant collagen in biomimicry and wound healing

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By Xiaolei Guo, Yi Zhang, Boxun Liu, Zhengbo Wen, Yuanbo Liu, Mengqi Zhou, Jiadao Wang, Tao Xu, Xiaoye Ran, Mengqing Zang
| Frontiers
Abstract Skin wound healing remains a major clinical challenge due to impaired regeneration and incomplete restoration of dermal architecture, creating the need for biomaterials that reconstruct the human extracellular matrix (ECM) microenvironment, especially the collagen-rich structural network. Current strategies to obtain human-relevant collagen primarily include genetically engineered recombinant collagen and ECM directly produced by human cells.
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