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Xiaoying Lv on Muck Rack

Xiaoying Lv

As seen in: MDPI, ACS Publications, BioRxiv, medRxiv
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Articles

Immuno-PET Imaging of Tumor Mesothelin Expression with a Gallium-68 Radiolabeled Nanobody

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By Xiaoying Lv, Xiangming Song, Yueling Deng, Danzha Zheng
| ACS Publications
Abstract Click to copy section linkSection link copied! Mesothelin (MSLN) is overexpressed in various solid tumors but limited in normal tissues, making it a promising candidate for molecular imaging and targeted therapy. Nanobodies, the smallest antibody derived fragments, are facile to modify for functional agent conjugation. With radionuclides, nanobody-based immunopositron emission tomography (immuno-PET) will provide valuable whole-body information for analysis of related target properties.
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Immuno-PET Imaging of Tumor Mesothelin Expression with a Gallium-68 Radiolabeled Nanobody

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By Xiaoying Lv, Yueling Deng, Xiangming Song, Danzha Zheng
| dx.doi.org
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GenVS TBDB: An Open AI-Generated and Virtual Screened Small-Molecule Database for Tuberculosis Drug Discovery

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By Xiaoying Lv, Han Guo, Xi Lu, Zhuo Tang
| BioRxiv
Abstract Tuberculosis (TB) remains a leading global health threat, with over 10 million new cases and 1.6 million deaths reported in 2021. Current TB therapies rely on a limited drug repertoire and prolonged treatment courses that have changed little in four decades. Here, we present GenVS-TBDB, an open AI-generated and virtual screened small-molecule database, which expands the chemical space against Mycobacterium tuberculosis (Mtb) essential proteins.
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