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Xiaoying Pei on Muck Rack

Xiaoying Pei

As seen in: BioRxiv
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Articles

GATA3 ZnF2-defective mutant condensation underlies type I IFN-activating in breast cancer

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By Yajie Wan, Xiaoying Pei, Tan Wang, Yatao Chen
| BioRxiv
Abstract Zinc finger (ZnF) transcription factors (TFs) consist of ZnF-containing DNA-binding domains (DBDs) and intrinsically disordered region (IDR)-containing activation domains (ADs).
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ROS Responsive Nanoparticles Encapsulated with Natural Medicine Remodel Autophagy Homeostasis in Breast Cancer

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By Xinhui Zhang, Heqi Gao, Daohe Wei, Xiaoying Pei
| dx.doi.org
In photodynamic therapy (PDT), elevated reactive oxygen species (ROS) activate tumor cell protective autophagy, therefore attenuating the antitumor function of therapy. Hence, inhibition of protective autophagy in tumors can improve the antitumor effect of PDT. Herein, an innovative nanotraditional Chinese medicine system ((TP+A)@TkPEG NPs), which remodeled autophagy homeostasis, was fabricated.
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