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Xiejunhao Zheng

As seen in: Frontiers in Immunology
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Identification of interleukin-11 as a comorbid risk factor for prostate cancer and Alzheimer’s disease using integrated bioinformatics and machine learning

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By Mengxue Wang, Yanrong Qian, Enyao Huang, Chunyan Chu, Tian Gao, Shengrong Chen, Na Zhao, Caichen Luo, Yifan Liu, Haowen Hu, Bowen Han, Ming Chen, Weipu Mao, Wenchao Li, Xiejunhao Zheng
| Frontiers in Immunology
Abstract Background: Prostate cancer (PCa) and Alzheimer’s disease (AD) are age-related disorders with a complex epidemiological association and limited therapeutic options. Identifying shared molecular drivers may reveal new treatment targets. Objective: To identify common transcriptomic signatures between PCa and AD and validate the role of interleukin-11 (IL11) as a functional comorbidity factor.
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