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Xiexia Huang on Muck Rack

Xiexia Huang

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Articles

Multi-omics fusion with machine learning enables robust prediction of treatment response in ovarian cancer for precision population health

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By Jie Chen, Yu Yang, Yue Wu, Mingqi Wang, Li Juan Su, Xiaohong Wei, Guiyang Xia, Huan Xia, Sheng Yi Lin, Mei Zhang, Tianshi Mao, Xiexia Huang
| Nature Verified
Abstract Inter-patient heterogeneity complicates predicting treatment response in ovarian cancer (OC). We developed OMICS-FUSE, an early-fusion multi-omics predictive model integrating proteomic, transcriptomic, and methylomic data from OC patients, evaluated across five machine learning algorithms with SHapley Additive exPlanations (SHAP) and experimental validation.
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