Xin Wei Chia on Muck Rack

Xin Wei Chia

As seen in: Nature
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Articles

Vulnerability of short-term memory in a mouse model of Alzheimer’s disease - Nature Communications

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By Chunyue Li, Xin Wei Chia, Guozhong Xu, Lee Fang Ang, Hiroshi Makino
| Nature Verified
Abstract Interference from distracting stimuli renders short-term memory vulnerable. While behavioral evidence suggests short-term memory deficits in Alzheimer’s disease (AD), the underlying neural mechanisms remain poorly understood. Using a mouse model of AD (APP-KI), we identified increased susceptibility of short-term memory to sensory perturbations.
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Emergence of cortical network motifs for short-term memory during learning - Nature Communications

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By Jian Tan, Tsukasa Kamigaki, Xin Wei Chia, Lee Fang Ang
| Nature Verified
Abstract Learning of adaptive behaviors requires the refinement of coordinated activity across multiple brain regions. However, how neural communications develop during learning remains poorly understood. Here, using two-photon calcium imaging, we simultaneously recorded the activity of layer 2/3 excitatory neurons in eight regions of the mouse dorsal cortex during learning of a delayed-response task.
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