Xinting Hu on Muck Rack

Xinting Hu

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Articles

PRMT1 facilitates the tumorigenesis of chronic lymphocytic leukemia by regulating methylation of MAST1

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By Zheng Tian, Pan Gao, Yang Zhang, Jun Ma, Hua Wang, Liyan Lu, Ya Zhang, Xin Wang, Xinting Hu
| Nature Verified
Abstract Protein arginine methyltransferase 1 (PRMT1) serves as a crucial regulator of post-translational modifications of proteins. While PRMT1 has been implicated in the progression of various cancers, its specific role in chronic lymphocytic leukemia (CLL) remains to be fully elucidated. This study aimed to investigate the oncogenic function of PRMT1 and assess the therapeutic efficacy of a selective PRMT1 inhibitor, C7280948, in CLL.
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