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Articles

Sarcopenia beyond muscle: endocrine–metabolic regulation and inter-tissue crosstalk across the muscle–tendon unit

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By Cai Jing, Xinxu Chen, Dongryeol Ryu, Shibo Wei, Guang Ta, Seung-Jun Jeong
| Frontiers
Abstract Sarcopenia is characterized by a progressive loss of muscle strength and physical performance that frequently exceeds the decline predicted by muscle mass alone. This discrepancy indicates that functional deterioration is shaped not only by the force-generating capacity of skeletal muscle, but also by the tissues responsible for transmitting and integrating that force.
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