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Xinying Guo on Muck Rack

Xinying Guo

As seen in: Nature, MDPI, Canadian Journal of Infectious Diseases & Medical Microbiology, Dove Medical Press, EIN News, JNeurosci
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Articles

Advanced glycation end products drive blood-brain barrier lipid dysregulation via RAGE-ABCA1 signaling to promote neurovascular dysfunction in Alzheimer’s disease

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By Firoz Akhter, Asma Akhter, Xinying Guo, Xiongwei Zhu, Zhen Zhao, Donghui Zhu
| Nature Verified
Abstract Neurovascular dysfunction is an early and critical contributor to Alzheimer’s disease (AD), yet the molecular mechanisms linking vascular pathology to metabolic dysregulation remain incompletely understood. Advanced glycation end products (AGEs), which accumulate during aging and metabolic stress, have been implicated in AD pathology; however, their role in cerebrovascular lipid homeostasis is unclear.
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Comparative analysis of quantitative fundus results of the left and right eyes and screening for coronary atherosclerotic disease: a binocular study

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By Zhenyan Wu, Xue Jiang, Yu Xin, Xinying Guo, Jie Zhang, WENYI ZHANG, Jian Liu, Yiran Wang, Saiguang Ling, Caixia Guo, Zibing Jin
| Nature Verified
Abstract Retinal microvascular parameters are potential biomarkers for systemic vascular health. This study aimed to assess the interocular consistency of these parameters in patients with coronary atherosclerotic disease(CAD) using AI-based quantitative analysis. We analysed 862 colour fundus photographs from 431 patients. Retinal vascular parameters—including fractal dimension (FD), vessel density (VD), and vessel diameters—were automatically measured using a ResNet 101-UNet deep learning model.
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Sevoflurane Ameliorates Autism-like Social Behavior by Restoring Excit

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By Haiping Xu, Ziwen Shi, Xinying Guo
| Dove Medical Press
Back to Journals » Drug Design, Development and Therapy » Volume 20 Authors Xu H , Shi Z, Guo X, Deng S, Wu M, Chen B, Qin J, Xu N, Zhao T, Chang Y, Song X Received 15 April 2025 Accepted for publication 3 February 2026 Published 25 February 2026 Volume 2026:20 Pages 1—17 DOI https://doi.org/10.2147/DDDT.S534484 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Prof.
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