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Xiongbo Sang

As seen in: Wiley Online Library, PLOS
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Articles

Pathological Glucose Levels Enhance Entry Factor Expression and Hepatic SARS‐CoV‐2 Infection

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By Guocheng Rao, Xiongbo Sang, Xinyue Zhu, Sailan Zou
| Wiley Online Library Verified
ACE2 angiotensin-converting enzyme 2 COVID-19 coronavirus disease 2019 DPP4 dipeptidyl peptidase-4 FURIN furin, paired basic amino acid cleaving enzyme GLP-1 glucagon-like peptide-1 mTOR mammalian target of rapamycin NAFLD nonalcoholic fatty liver disease NRP1 neuropilin-1 PA palmitic acid RG4 RNA G-quadruplex SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 SGLT2 sodium-glucose cotransporter-2 TMPRSS2 transmembrane serine protease 2 TMPRSS4 transmembrane serine protease 4 VSV...
Open in Who Shared Issue with article?

Targeting RNA G-quadruplex with repurposed drugs blocks SARS-CoV-2 entry

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By Geng Liu, Xinyue Zhu, Qiyu Tong, Xiongbo Sang, PLOS Pathogens
| PLOS
A drug-repurposing screening identifies TPT and BBM as RG4-targeting agents Our data presented in this and previous studies [17] collectively demonstrated the existence of RG4 in at least four host factors (Ace2, Axl, Furin, and Tmprss2) that are considered as potential therapeutic targets for COVID-19.
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