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Xite Lin

As seen in: Nature, MDPI, Dove Medical Press
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Articles by Xite Lin

Metabolic activation of LDHA by ERRα represses inflammasome-dependent pyroptosis and promotes ovarian cancer chemoresistance

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By Yuan Ren Verified, Jingxuan Ye, Yonghong Zhang, Guanyu Ruan, Jincheng Ma, Hao Lin, Liang Wang, Liying Wang, Xite Lin, Nan Wang, Xiaodan Mao, Pengming Sun, Yashi Shi, Maotong Zhang
| Nature Verified
Abstract Chemoresistance remains a major unmet challenge in the clinical management of ovarian cancer. As a metabolism-associated malignancy, the poor prognosis and frequent chemoresistance of ovarian cancer are closely linked to metabolic reprogramming. In this study, we identify estrogen-related receptor α (ERRα) as a key regulator of metabolic plasticity and chemoresistance in ovarian cancer.
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Patients with mismatch repair deficiency endometrial cancer

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By Jincheng Ma, Xite Lin, Yuan Ren Verified, Jiansong Lin
| Dove Medical Press
Back to Journals » Journal of Inflammation Research » Volume 17 Authors Ma J , Lin J, Lin X , Ren Y, Liu D, Tang S, Huang L, Xu S, Mao X , Sun P Received 6 December 2023 Accepted for publication 20 March 2024 Published 2 April 2024 Volume 2024:17 Pages 2039—2050 DOI https://doi.org/10.2147/JIR.S453337 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 3 Editor who approved publication: Professor Ning Quan Jincheng Ma,1– 3,* Jiansong Lin,4,* Xite...
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Current Oncology | Free Full-Text | Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Is Associated with Cervical Stromal Involvement in Endometrial Cancer Patients: A Cross-Sectional Study in South China

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By Chunxia Chen, Tingting Jiang, Jincheng Ma, Xite Lin
| MDPI
4. Discussion In this study, we demonstrated that MAFLD is an independent factor associated with CSI in EC patients. In the type I EC group, there was a link between MAFLD and CSI, but in the type II EC group, there was no evidence of such an association. We further demonstrated that HSI may serve as a predictor of CSI in type I EC patients without T2DM. Over the past decades, the prevalence of MAFLD/NAFLD has increased dramatically worldwide.
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