Liying Wang
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Metabolic activation of LDHA by ERRα represses inflammasome-dependent pyroptosis and promotes ovarian cancer chemoresistance
Abstract Chemoresistance remains a major unmet challenge in the clinical management of ovarian cancer. As a metabolism-associated malignancy, the poor prognosis and frequent chemoresistance of ovarian cancer are closely linked to metabolic reprogramming. In this study, we identify estrogen-related receptor α (ERRα) as a key regulator of metabolic plasticity and chemoresistance in ovarian cancer.
Halogen-Driven Electronic Modulation of Single-Atom Fe Sites for Universal Non-Radical Catalysis
R.Lv, L.Wang, N.Xu, Z.Zhao, and G.Li, “Halogen-Driven Electronic Modulation of Single-Atom Fe Sites for Universal Non-Radical Catalysis.” Advanced Materials (2026): e73634. https://doi.org/10.1002/adma.73634 Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Recent Advances in Bimetallic Site Catalysts for Photocatalytic Ammonia Synthesis: Synergistic Effects and Design Strategies
1 Introduction Ammonia (NH3), one of the crucial basic chemicals, is widely used in fields such as chemical fertilizers, refrigerants, explosives, and chemical raw materials [1]. Currently, the industrial production of ammonia primarily relies on the Haber–Bosch process, which uses iron-based catalysts to synthesize ammonia under high temperatures (400°C–500°C) and high pressures (10–15 MPa) [2].
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