Xixi Ning on Muck Rack

Xixi Ning

As seen in: Royal Society of Chemistry
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Articles

Core Fucosylation of Maternal Milk N-Glycans Imparts Early-life Immune Tolerance through Gut Microbiota-dependent Regulation on RORγt+ Treg Cells

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By Yuyuan Li, Xixi Ning, Zihui Zhao, Qidi Xue
| Royal Society of Chemistry
Core Fucosylation of Maternal Milk N-Glycans Imparts Early-life Immune Tolerance through Gut Microbiota-dependent Regulation on RORγt+ Treg Cells Milk glycans play key roles in shaping and maintaining a healthy infant gut microbiota. Core fucosylation catalyzed by fucosyltransferase (Fut8) is the major glycosylation pattern on human milk N-glycan, which was crucial for promoting the colonization and dominant growth of Bifidobacterium and Lactobacillus spp. in neonates.
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