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Xiyin Wang on Muck Rack

Xiyin Wang

As seen in: Nature, Wiley Online Library, MDPI, Taylor & Francis Online, Texas Medical Center
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Articles

Novel (Z)-endoxifen-related new chemical entities exhibit potent anti-cancer activity in ERα+ breast cancer

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By Lena Batoon, Xiyin Wang, Michael E. Emch, Sandra S. Hammer, Steven Quay, Matthew Goetz, John Hawse, Rajeev S. Muthyala, Esther Rodman, Sofia Marigliano, Anna Detry, Mohsen Sadatrezaei
| Nature Verified
Abstract Approximately 80% of breast cancers express estrogen receptor alpha (ERα), yet ERα-positive disease remains associated with high recurrence and late relapse. (Z)-Endoxifen (ENDX), the most abundant active metabolite of tamoxifen, is a potent, orally bioavailable, selective estrogen receptor modulator currently in development for breast health indications.
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Insights into the genetic basis of natural selection and domestication from Sorghum

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By Hui Guo, Dong Zhang, Xiyin Wang, Tae-Ho Lee, Andrew H. Paterson
| Nature Verified
Abstract Analysis of gene sequences showing signatures of selection can provide insights into the evolution and domestication of an organism and can suggest ways to accelerate crop improvement. Using whole-genome resequencing and RNA-seq-derived SNP data from 69 diverse sorghum accessions, we characterized genetic variation and identified genes showing evidence of potentially important roles in sorghum domestication and adaptation.
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Identification of Immunophenotypes as a Mediator of Gut Microbiota‐Driven Female Anovulation‐Induced Infertility: A Mediation Mendelian Randomization Study

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By Xiyin Wang, Xianyuan Yi, Duozhen Chen
| Wiley Online Library Verified
Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
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