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Xiying Chen

As seen in: Nature, Wiley Online Library
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Articles

Repeated tDCS of the left dorsolateral prefrontal cortex for acute DoC: a pilot randomized controlled trial

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By Hui Ma, Chenggong Hu, Cheng Huang, Ziqi Zhang, Xiying Chen, Chengsen Jia, Kehong Zhao, Xianrui Hu
| Nature Verified
Abstract This study aimed to investigate the safety and feasibility of transcranial direct current stimulation (tDCS) in patients with acute disorders of consciousness (DoC), and to preliminarily explore its potential intervention effects. In this sham-controlled randomized trial, participants with acute DoC within 7–28 days post-onset were randomly assigned (1:1) to either the active or sham stimulation group.
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Stiff matrix-induced KRTAP2-3 expression suppresses ciliogenesis via actin tension-driven chromatin remodeling

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By Xiying Chen, Li Yi, Guangsong Xie, Hao Jin, Feng Yang, Wenjian Cao, Zhouyuanjing Shi, Zhangqi Xu, Chunxiao Huo, Aifu Lin, Wei Liu, Guangshuo Ou, Tianhua Zhou, Baohua Ji, Shanshan Xie, Shucan Li
| Nature Verified
Abstract Primary cilia are sensory organelles that project from the cell surface and play vital roles in cell signaling pathways essential for development and homeostasis. However, the mechanotransduction pathways through which cells perceive and respond to matrix rigidity to regulate ciliogenesis remain poorly understood. In this study, we find that increased matrix stiffness significantly reduces primary cilia formation compared to soft matrix.
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Deciphering cilia and ciliopathies using proteomic approaches

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By Feng Yang, Tianhua Zhou, Xiying Chen, Zhouyuanjing Shi
| Wiley Online Library Verified
Abbreviations ADCY3 adenylate cyclase 3 ADPKD autosomal dominant polycystic kidney disease AHI1 Abelson helper integration site 1 ARL13B ADP ribosylation factor-like GTPase 13B B9d1 B9 domain containing 1 BBS Bardet–Biedl syndrome CA central apparatus Cc2d2a coiled-coil and C2 domain containing 2A CCP110 centriolar coiled-coil protein 110 cELVs ciliary extracellular-like vesicles CEP164 centrosomal protein 164 CEP290 centrosomal protein 290 CEP97 centrosomal protein 97 EVs extracellular...
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