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Full article: 16S rRNA Gene Sequencing Combined with Metabolomics to Explore Intestinal Flora and Metabolic Changes in Young Febrile Rats and the Mechanism of Xiangqin Jiere Granules
Abstract Purpose Xiangqin Jiere Granules (XQJRG), a Chinese patent medicine used to treat acute fever in children caused by colds, seasonal flu, and coronavirus disease 2019 has been proven to have antipyretic and anti-inflammatory effects in young febrile rats. Fever is known to affect the host-gut microbiota crosstalk. However, the pharmacological mechanism of XQJRG in this regard remains unclear.
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