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Xu Chen

As seen in: AIChE Journal, Nature, Wiley Online Library, Memory Studies, New Phytologist, PLOS, PLOS ONE, BMJ Open, Frontiers, Frontiers in Immunology and
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Articles

The Factors Associated with the Health-Related Quality of Life in Pregnant Women in the second and Third Trimesters: Evidence from Jiangsu Province, Eastern China

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By Lianshuai Zheng, Xu Chen, Yao Meng
| Taylor & Francis Online
Abstract Purpose The health-related quality of life (HRQoL) of pregnant women has received much attention. Understanding the factors affecting their HRQoL will help health care providers develop targeted strategies for pregnancy care. This study investigated the current status of pregnant women’s HRQoL in Jiangsu Province, Eastern China, explored the impact of chronic pain and other factors on it.
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Macrophage INSIG1 deficiency drives psoriasiform dermatitis via the SREBP2-STAT1 axis

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By Xiangzheng Li, Yu Zang, shaowen Liu, Leyi Chen, Xiaohe Xu, Lin Wang, Rongzhuo Long, Mengfan Zhang, Xu Chen, Lei Qiang, Yuan He, Tiancheng Sheng
| Nature Verified
Abstract Psoriasis is an autoimmune skin disease, and its pathogenesis remains incompletely understood. As central drivers of psoriasis pathogenesis that bridge innate and adaptive immunity, macrophages are known to be modulated in their function by insulin-induced gene 1 (INSIG1), a regulator of cholesterol synthesis. Bioinformatic analysis of human psoriatic lesions reveals a significant negative correlation between INSIG1 expression and pro-inflammatory cytokine levels (IL-23, IL-17A).
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Deep learning-based semantic segmentation of night-sky clouds for operational telescope scheduling

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By Xuan Liu, Hai Cao, Ruojun Wang, Shaoming Hu, Difu Guo, Xu Chen
| Nature Verified
Abstract Ground-based optical telescopes necessitate prompt and spatially detailed information regarding dome-scale cloud coverage to facilitate target-specific shuttering and scheduling decisions. When only coarse or delayed atmospheric data are available, observatories risk inefficient use of scarce dark time and the irreversible loss of scientific exposures.
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