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Xue-Ying Tan on Muck Rack

Xue-Ying Tan

As seen in: Taylor & Francis Online, Dove Medical Press
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Articles

Chitosan Oligosaccharide-Functionalized Ruthenium-Curcumin Nanodots for Targeted Therapy of Acute Kidney Injury

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By Qin Yu, Xue-Ying Tan, Xian Liu
| Taylor & Francis Online
Abstract Background Acute kidney injury (AKI) is a critical clinical syndrome with high morbidity and mortality, primarily driven by mitochondrial oxidative stress and tubular epithelial cell apoptosis. Current antioxidant therapies are limited by poor bioavailability and lack of renal specificity. To address this, we developed a dual-targeting nanomedicine based on ultrasmall chitosan oligosaccharide-functionalized ruthenium-curcumin nanodots (LMWC/Ru-Cur).
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