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Xuedie Gu

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Articles

Chromosomal fusions trigger rediploidization of autopolyploid genomes

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By Chuanshuai Xie, Chaowei Zhou, Kexin Ma, Haoyu Wang, Jiahong Wu, Yan Zhou, Yongrui Lu, Da Ji, He Gao, Weiqiang Li, Zhaofang Han, Shijun Xiao, Benhe Zeng, Jiangong Niu, Tao Zhang, Jian Shen, Chunna Liu, Jing Luo, Daniel J Macqueen, Axel Meyer, Haiping Liu, Luohao Xu, Zitu Ma, Xuedie Gu, Suxing Fu, Sheng’ao Chen
| Nature Verified
Abstract The ancestor of all vertebrates is thought to have undergone autopolyploid whole-genome duplication (WGD)1,2, doubling the genetic raw material for evolutionary diversification3,4,5. However, we still do not understand the first steps of rediploidization that followed, required for the emergence and divergence of duplicated genes (ohnologues) created by WGD6,7. Consequently, how the functional potential created by autopolyploidy becomes realized during evolution remains unclear.
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