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Articles by Xueming Wu
Nighttime intensive care unit admission increased 30-day mortality in sepsis patients: a retrospective propensity-score matched analysis based on MIMIC-IV database
Abstract Although there has been extensive research on the mortality and prognosis of sepsis, none of them has been focused on the association between mortality and timing of admission to intensive care unit (ICU) in sepsis patients. This study used MIMIC-IV data to compare mortality risk between daytime and nighttime ICU admission in sepsis patients. Propensity score matching (PSM) balanced baseline characteristics. Kaplan–Meier survival analysis and multivariable Cox regression were performed.
[2601.04191] Embedding Autonomous Agents in Resource-Constrained Robotic Platforms
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The Chemo-Enzymatic Synthesis of 8,9-Dihydrohydroxysafflor Yellow A and Its Neuroprotective Effects against Cerebral Ischemia-Reperfusion Injury
Abstract Click to copy section linkSection link copied! Hydroxysafflor yellow A (HSYA), the principal bioactive compound of safflower, is clinically used for ischemic cerebrovascular disease. However, the current sources of HSYA are limited and inadequate for clinical applications. In this study, we synthesized 8,9-dihydrohydroxysafflor yellow A (dh-HSYA), an analogue of HSYA, via a chemo-enzymatic approach and investigated its neuroprotective activity.
Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation
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