Xueying Jiang

Near-infrared light-triggered covalent nanodrug for combined singlet oxygen therapy and photothermal therapy Endoperoxides, which can liberate singlet oxygen via cycloreversion reactions, represent a promising strategy for cancer therapy.

Quinoa is a nutrient-rich pseudocereal with a lower glycemic index and glycemic load. However, its therapeutic potency and underlying mechanism against insulin resistance (IR) have not been fully elucidated. In this work, network pharmacology was applied to screen IR targets and their related pathways. The efficacy and mechanism of black quinoa polyphenols (BQP) on IR improvement were evaluated and uncovered based on the IR model in vitro combined with molecular docking.

Diabetes is the third major noncommunicable disease that threatens human health after cancer and cardiovascular disease, usually accompanied by other series complications including diabetic cardiovascular complications, kidney complications, and neuropathy. (1) In 2019, the number of diabetics was about 463 million, which will reach 702 million by 2045 reported by the International Diabetes Federation.