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Xueying Zhan

As seen in: Nature, Wiley Online Library, BioRxiv
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Articles

Molecular landscape of the fungal plasma membrane and implications for antifungal action - Nature Communications

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By Jennifer Jiang, Mikhail V. Keniya, Xueying Zhan, Huan Wang, Haiyan Zheng, Erika Shor, Zheng Shi, Min Xu, David S Perlin, Cynthia Pang
| Nature Verified
Abstract Fungal plasma membrane proteins represent key therapeutic targets for antifungal agents, yet their native structure and spatial distribution remain poorly characterized. Herein, we employ an integrative approach to investigate the organization of plasma membrane protein complexes in Candida glabrata, focusing on two abundant and essential membrane proteins, the β-(1,3)-glucan synthase (GS) and the proton pump Pma1.
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Structural and Biophysical Dynamics of Fungal Plasma Membrane Proteins and Implications for Echinocandin Action in Candida glabrata

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By Jennifer Jiang, Mikhail V. Keniya, Xueying Zhan, Anusha Puri
| BioRxiv
Abstract Fungal plasma membrane proteins represent key therapeutic targets for antifungal agents, yet their structure and spatial distribution in the native context remain poorly characterized. Herein, we employ an integrative multimodal approach to elucidate the structural and functional organization of plasma membrane protein complexes in Candida glabrata, focusing on prominent and essential membrane proteins, the polysaccharide synthase β-(1,3)-glucan synthase (GS) and the proton pump Pma1.
Open in Who Shared Issue with article?

CryoMAE: Few-Shot Cryo-EM Particle Picking with Masked Autoencoders

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By Xueying Zhan, Min Xu
| arxiv.org
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