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Optimal timing for frozen-thawed embryo transfer: evidence from a systematic review and meta-analysis
Abstract Aim: This study aims to evaluate the association between the duration of cryopreservation and reproductive and neonatal outcomes using a meta-analysis. Methods: A comprehensive search was conducted in PubMed, Embase and Medline databases up to October 1, 2025. A total of 17 studies were included in the analysis and compared reproductive/neonatal outcomes between frozen-thawed embryo transfer (FET) ≤12 vs >12 months post-storage.
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