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Yali Ci

As seen in: Wiley Online Library, MDPI
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Articles

Flavivirus Concentrates Host ER in Main Replication Compartments to Facilitate Replication

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By Yali Ci, Kai Han, Jie Kong, Shuhan Huang
| Wiley Online Library Verified
1 Introduction Both DNA and RNA viruses establish replication compartments (RCs, or replication organelles/factories) to create environments that facilitate viral genome replication.[1, 2] Many RNA viruses remodel cellular organelles to generate membranous vesicles as viral RCs for efficient viral replication and evasion of host immune recognition and intervention3] The endoplasmic reticulum (ER), the central hub of protein and lipid biosynthesis in the cell, is often hijacked by...
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Exploration of the Shared Molecular Mechanisms between COVID-19 and Neurodegenerative Diseases through Bioinformatic Analysis

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By Yingchao Shi, Wenhao Liu, Yali Ci
| MDPI
Abstract : The COVID-19 pandemic has caused millions of deaths and remains a major public health burden worldwide. Previous studies found that a large number of COVID-19 patients and survivors developed neurological symptoms and might be at high risk of neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).
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