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Frontiers | Hypersensitive C-reactive protein-atherogenic index as a novel marker for metabolic dysfunction-associated steatotic liver disease in type 2 diabetes mellitus
Introduction Metabolic dysfunction-associated steatotic liver disease (MASLD), previously named non-alcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated fatty liver disease (MAFLD), was characterized as excessive triglyceride (TG) accumulation in hepatocytes and has been demonstrated as the leading cause of liver-related morbidity and mortality (1).
A CRISPR/Cas9-Engineered Mouse Carrying a Conditional Knockout Allele for the Early Growth Response-1 Transcription Factor
Early growth response 1 (EGR1) mediates transcriptional programs that are indispensable for cell division, differentiation and apoptosis in numerous physiologies and pathophysiologies. Whole-body EGR1 knockouts in mice (Egr1KO) have advanced our understanding of EGR1 function in an in vivo context.
"A Mouse Model for Conditional Expression of Activated β-Catenin in Epi" by Vineet K Maurya, Yan Ying et al.
Publication Date 10-1-2024 Journal Transgenic Research DOI 10.1007/s11248-024-00402-z PubMedCentral® Posted Date 8-7-2024 PubMedCentral® Full Text Version Post-print Published Open-Access yes Keywords Animals, beta Catenin, Keratinocytes, Mice, Doxycycline, Epidermis, Mice, Transgenic, Cell Proliferation, Hair Follicle, Keratin-5, Female Abstract We report the generation and characterization of the K5: CAT bigenic mouse in which the constitutively activated form of β-catenin (ΔN89 β-catenin)...
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