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Articles by Yang Pei
A Novel Four-Gene Signature Stratifies Prognosis and Reflects the Immune Landscape in Colorectal Cancer
You are already at the latest version Background: Colorectal cancer (CRC) exhibits significant molecular heterogeneity, leading to diverse clinical outcomes and highlighting the need for more accurate prognostic biomarkers. This study aimed to identify a novel gene signature to improve risk stratification and to explore its underlying biological relevance, particularly in relation to the tumor immune landscape.
Covalent versus Dimeric Optimization of Nectin-4-Targeted Peptide Radiotracers: A Head-to-Head Comparison in Triple-Negative Breast Cancer Mice Models Click to copy article link Article link copied!
Cite Jump to ExpandCollapse ArticleMarch 26, 2026 Covalent versus Dimeric Optimization of Nectin-4-Targeted Peptide Radiotracers: A Head-to-Head Comparison in Triple-Negative Breast Cancer Mice Models Click to copy article linkArticle link copied! Yang Pei Yang Pei China Isotope & Radiation Corporation, Beijing 100089, China HTA Co., Ltd., Beijing 102413, China Xu Zhou Xu Zhou HTA Co., Ltd., Beijing 102413, China Fei Gao Fei Gao HTA Co., Ltd., Beijing 102413, China Mingyue Sun Mingyue Sun HTA...
Design and Evaluation of a 68Ga-Labeled Dimeric Cyclic Peptide as a Large-Volume Linker Strategy for Balancing Affinity and Retention in CXCR4-Targeted PET Imaging
Abstract Click to copy section linkSection link copied! CXCR4 is overexpressed in various malignancies and represents an attractive target for PET imaging. However, currently available peptide-based tracers often exhibit rapid clearance and a narrow imaging window, which limit their clinical implication.
Deciphering Multidrug-Resistant Pseudomonas aeruginosa: Mechanistic Insights and Environmental Risks
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Global perspectives on anti-feminism: far-right and religious attacks on equality and diversity
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A Comparison of Structural Variant Calling from Short-Read and Nanopore-Based Whole-Genome Sequencing Using Optical Genome Mapping as a Benchmark
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Controlling the Superconducting Critical Temperature and Resistance of NbN Films through Thin Film Deposition and Annealing
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Aerospace | Free Full-Text | Gliding Footprint Calculation Method for Aircraft with Thrust Failure Based on Six-Degree-of-Freedom Flight Envelope and Back-Propagation Artificial Neural Network
1. Introduction Aircraft survivability is defined as the ability of an aircraft to avoid and/or withstand hostile environments [1]. Attacks from air defense and terrorist weapons can bring in-flight damage to aircraft [2,3,4]. An attrition kill (the loss of aircraft) occurs when the aircraft loses one or more essential functions (i.e., structural integrity, lift, thrust, and control) for flight [1].
Use of genome sequencing to hunt for cryptic second-hit variants: analysis of 31 cases recruited to the 100 000 Genomes Project
Discussion While the 100kGP has provided both new diagnoses and new research insights in rare inherited disease, many patients still lack a genetic diagnosis. Clinical pipelines and tiering strategies such as those used in the 100kGP analysis are inevitably biased towards exonic variants, where there is a much larger body of evidence when annotating potential pathogenicity.
Use of genome sequencing to hunt for cryptic second-hit variants: analysis of 31 cases recruited to the 100 000 Genomes Project
diagnosis genetic diseases, inborn genetics, medical sequence analysis, DNA genomics WHAT IS ALREADY KNOWN ON THIS TOPIC Although it is known that whole genome sequencing can uncover cryptic structural variants (SVs) and deep intronic splice variants, most ‘second-hit’ studies in the current literature are limited to specific genes or disease areas.
Recent Progress in Polymeric AIE-Active Drug Delivery Systems: Design and Application
Aggregation-induced emission (AIE) provides a new opportunity to overcome the drawbacks of traditional aggregation-induced quenching of chromophores. The applications of AIE-active fluorophores have spread across various fields. In particular, the employment of AIEgens in drug delivery systems (DDSs) can achieve imaging-guided therapy and pharmacodynamic monitoring.
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