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Genetic variability and phylogenetic analysis of the long control region in human papillomavirus types 18 and 51 from central China - Virology Journal
In this study, PCR amplification and sequencing were performed on 55 HPV-18 single-positive samples, yielding 43 complete LCR sequences. The remaining 12 samples were excluded due to PCR amplification failure or suboptimal sequencing quality. Genetic variation analysis of HPV-18 LCR sequences identified 17 SNP sites. The results were shown in Table 3. Compared with the HPV-18 reference sequence, the LCR exhibited a nucleotide variation rate of 100%.
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