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Articles by Yanting Chen
Mitochondrial complex IV disruption is a detrimental pathology conferring ssusceptibility to alzheimer’s disease
Abstract Mitochondrial complex IV (CIV) is an integral part of the mitochondrial electron transport chain (ETC) and plays a pivotal role in maintaining mitochondrial function. In contrast to the long-standing recognition of its dysfunction in Alzheimer’s disease (AD), the exact role of CIV deficit in the pathogenesis of this neurodegenerative disorder remains poorly defined.
Disrupted synaptic vacuolar H + -ATPase renders synaptic vulnerability to Alzheimer’s disease
Abstract Defective synaptic transmission is a prominent pathology that underlies cognitive deficits in Alzheimer’s disease (AD), highlighting the need to elucidate molecular mechanisms of synaptic failure. Vacuolar H+-ATPase (V-ATPase), a proton-pumping enzyme, is essential for synaptic vesicle acidification and neurotransmitter loading. However, whether SV-associated V-ATPase is vulnerable to AD remains unclear.
D-allose reprogrammes the mitophagy–mtDNA–cGAS–STING–ADM2 axis to restore nucleus pulposus cell homeostasis in intervertebral disc degeneration
Abstract Intervertebral disc degeneration (IVDD) is driven by progressive loss of nucleus pulposus cell (NPC) homeostasis, yet the stress-responsive mechanisms governing this process remain incompletely defined.
The myeloid IL-1 receptor limits IL-27-mediated endothelial type I IFN during nephrotoxic serum nephritis
ResearchImmunologyInflammationNephrology Open Access | 10.1172/jci.insight.200728 JCI Insight. https://doi.org/10.1172/jci.insight.200728. Copyright © 2026, Chen et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Persistent perinatal protein malnutrition and post-weaning high-fat diet induce metabolic syndrome and hepatic UCP2 overexpression in IUGR offspring
Abstract Introduction: Adults born with intrauterine growth restriction (IUGR) are at a significantly increased risk of developing metabolic syndrome. Postnatal nutritional patterns are critical modifiers of this risk. This study investigated the effects of different perinatal nutritional interventions on glucose/lipid metabolism and hepatic steatosis in IUGR offspring, and explored the role of hepatic uncoupling protein 2 (UCP2).
Systematically Engineering Escherichia coli for Efficient and Complete Hydroxytyrosol Biosynthesis Click to copy article link Article link copied!
Abstract Click to copy section linkSection link copied! Hydroxytyrosol (HT), a potent natural antioxidant in olive oil, has broad food and nutraceutical applications, but sustainable, scalable production remains challenging. Here, we achieved efficient de novo HT biosynthesis in Escherichia coli using glucose-glycerol dual carbon sources, combining metabolic engineering and rational enzyme design.
Interventions to reduce occupational burnout in general practitioners: a systematic review and meta-analysis protocol
Abstract Background: General practitioners (GPs) are at high risk of burnout, which threatens physicians’ mental health, care quality, and the sustainability of primary health care systems. Although a growing number of interventions have been developed to prevent or reduce burnout among GPs, their effectiveness and the mechanisms through which they work remain unclear.
Does FinTech reduce human biases? Evidence from advisory vs. automated FinTechs in lending
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Intraocular lens power calculation for combining cataract and pterygiu
Back to Journals » Clinical Ophthalmology » Volume 20 Original Research Cataract Authors Li Z , Tan B, Chen Y, Liu R, Wang H, Kuang J, Luo F, Zeng M Received 26 October 2025 Accepted for publication 5 February 2026 Published 17 February 2026 Volume 2026:20 Pages 1—8 DOI https://doi.org/10.2147/OPTH.S575469 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Bharat Gurnani Lens Power Calculation in Cataract And...
Characterization and Expression Patterns of Heat Shock Protein 70 Genes from Paracoccus marginatus in Response to Temperature and Insecticide Stress
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Pricing Decisions in Dual-Channel Supply Chains Considering the Offline Channel Preference and Service Level
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Yanting Chen SciProfiles Scilit Preprints.org Google Scholar and Mengling Wu SciProfiles Scilit Preprints.org Google Scholar * Business School, University of Shanghai for Science and Technology, Shanghai 200093, China * Author to whom correspondence should be addressed.
Analysis of Binding Modes between Three Perfluorosulfonates and GPER Based on Computational Simulation and Multiple Spectral Methods
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
AMPK Suppression Due to Obesity Drives Oocyte mtDNA Heteroplasmy via ATF5‐POLG Axis
1 Introduction In recent decades, obesity (OB) has become a pandemic.[1] Particularly, over two-thirds of females at their reproductive age are either overweight or OB, and the number shows no signs of decline.[2] Beyond its impacts on metabolic health, female OB at reproductive age also reduces oocyte quality,[3] contributing to decreased fertility rates worldwide, even in conjunction with assisted reproductive techniques like in vitro fertilization.[4] Besides, the suboptimal oocyte...
Improved NH3-SCR activity by the cooperation of FeVO4 and CeO2 nanosheet catalysts: Structure and mechanism
Improved NH3-SCR activity by the cooperation of FeVO4 and CeO2 nanosheet catalysts: Structure and mechanism Yuqiu Liu, Biyi Huang, Jianyi Zhang, Yanting Chen, Jinsheng Chen and Jinxiu Wang Abstract A series of FeVO4/CeO2 nanosheet catalysts featuring various mass percentages (x%) of FeVO4 (denoted x%FeV/CeO2-S) were synthesized and employed in selective catalytic reduction of NOx with NH3.
Promotion of Photocatalytic Hydrogen Production by Utilization of Triplet Excited States of Organic Dyes and Adjustment of π-π Interactions
Promotion of Photocatalytic Hydrogen Production by Utilization of Triplet Excited States of Organic Dyes and Adjustment of π-π Interactions Siwei Liu, Qian Chen, Yanting Chen, Peixuan Lin, Zhanghangyu Zhu, Mengmeng Han, zhian lan, Xiong Chen, Xinchen Wang, Qianqian Li and Zhen Li Abstract Dye/polymeric carbon nitride (PCN) systems exhibited great potentials for photocatalytic hydrogen evolution (PHE), due to the broad light-harvesting region and optimized charge separation ability.
Daridorexant for the treatment of insomnia disorder: A systematic review and meta-analysis of randomized controlled trials.
Daridorexant is a novel dual orexin receptor antagonist that has shown efficacy as a treatment for insomnia in multiple randomized clinical trials. However, the efficacy and safety of daridorexant for treatment of insomnia disorder has not been characterized comprehensively in the literature. Therefore, we performed a meta-analysis of available studies. We performed a meta-analysis to systematically evaluate the efficacy and safety of daridorexant for treatment of insomnia disorder.
Promotional effect of Fe and Ce co-doping on the V2O5-WO3/TiO2 catalyst for SCR of NOx with high K and Pb resistance
Promotional effect of Fe and Ce co-doping on the V2O5-WO3/TiO2 catalyst for SCR of NOx with high K and Pb resistance Xianfang Yi, Jinxiu Wang, Yuqiu Liu, Yanting Chen and Jinsheng Chen Abstract There is an increasing demand to develop efficient SCR deNOx catalysts with high resistance to alkali and heavy metal.
Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice
Abstract The obesity rate is rapidly increasing, which has been attributed to lack of exercise and excessive energy intake. Here, we found a previously unidentified explanation, due to lack of maternal exercise. In this study, healthy maternal mice were assigned either to a sedentary lifestyle or to exercise daily, and fetal brown adipose tissue (BAT) development and offspring metabolic health were analyzed.
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