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Yanying Sun on Muck Rack

Yanying Sun

As seen in: Wiley Online Library, Oxford Academic, MDPI, ACS Publications, BioRxiv
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Articles

Membrane Tethering of Honeybee Antimicrobial Peptides in Drosophila Enhances Pathogen Defense at the Cost of Stress‐Induced Host Vulnerability

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By Yanan Wei, Yanying Sun, Xinyue Zhou, Doyoun Kim
| Wiley Online Library Verified
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description cbic70040-sup-0001-SuppData-S1.zip30 MB Supplementary Material References 1, , Nat. Biotechnol. 2006, 24, 1551. 2, , , , Front. Cell. Infect. Microbiol. 2016, 6, 194. 3, , , , , , , Mil. Méd. Res. 2024, 11, 7. 4, , , , , , , , , , , , Arch. Dermatol. Res. 2023, 315, 2623. 5, , , , , , Antimicrob. Agents Chemother. 1999, 43, 782.
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Genetic Screening Reveals Cone Cell-Specific Factors as Common Genetic Targets Modulating Rival-Induced Prolonged Mating in male Drosophila melanogaster

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By Woo Jae, Zhengzhou Henan, Yanying Sun
| Oxford Academic Verified
Male-male social interactions exert a substantial impact on the transcriptional regulation of genes associated with aggression and mating behavior in male Drosophila melanogaster. Throughout our comprehensive genetic screening of aggression-related genes, we identified that the majority of mutants for these genes are associated with rival-induced and visually-oriented mating behavior, longer-mating-duration (LMD).
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Investigating the antimicrobial and immunomodulatory effects of honeybee venom peptide apamin in the Drosophila genetic platform.

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By Yanan Wei, Wenjie Jia, Yanying Sun, Tianmu Zhang
| BioRxiv
Abstract Apamin, an 18-amino acid peptide neurotoxin, constitutes a significant portion of honeybee venom. Although traditionally recognized for its neurotoxic effects, our research demonstrates that apamin exhibits potent antimicrobial properties when genetically expressed in Drosophila. The antimicrobial efficacy of apamin is independent of its disulfide bonds and is enhanced when the peptide is membrane-tethered.
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