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Yasaman Barekatain on Muck Rack

Yasaman Barekatain

As seen in: Texas Medical Center
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Articles

Comparative Pharmacology of a Bis-Pivaloyloxymethyl Phosphonate Prodrug Inhibitor of Enolase after Oral and Parenteral Administration

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By Victoria Yan, Yasaman Barekatain, Yu-Hsi Lin, Nikunj Satani
| Texas Medical Center
Metabolically labile prodrugs can experience stark differences in catabolism incurred by the chosen route of administration. This is especially true for phosph(on)ate prodrugs, in which successive promoiety removal transforms a lipophilic molecule into increasingly polar compounds.
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Therapeutic potential of PRMT5 and MAT2A as synthetic lethal targets in MTAP-deficient GBM tumors

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By Yasaman Barekatain
| Texas Medical Center
Author ORCID Identifier 0000-0002-4454-1496 Document Type Dissertation (PhD) Program Affiliation Medical Physics Degree Name Doctor of Philosophy (PhD) Advisor/Committee Chair Raghu Kalluri, M.D., Ph.D Committee Member Florian Muller, Ph.D. Committee Member Ronald DePinho, M.D. Committee Member Pratip Bhattacharya, Ph.D Committee Member John de Groot, M.D. Committee Member Jason Huse, M.D., Ph.D Committee Member Yonathan Lissanu, M.D., Ph.D Abstract Homozygous deletion of methylthioadenosine...
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