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Impaired insight in schizophrenia is associated with higher frontoparietal cerebral blood flow: an arterial spin labeling study - Schizophrenia
Abstract Impaired insight into illness occurs in up to 98% of patients with schizophrenia, depending on the stage of illness, and leads to negative clinical outcomes. Previous neuroimaging studies suggest that impaired insight in patients with schizophrenia may be related to structural and functional anomalies in frontoparietal brain regions. To date, limited studies have investigated the association between regional cerebral blood flow (CBF) and impaired insight in schizophrenia.
390. Evaluation of the Glymphatic System in Schizophrenia Using 1H-MRS and MRI
Research Imaging Centre, Centre for Addiction and Mental Health (CAMH), Institute of Medical Science, University of Toronto
Cortical thinning in relation to impaired insight into illness in patients with treatment resistant schizophrenia - Schizophrenia
Abstract Impaired insight into illness is a common element of schizophrenia that contributes to treatment nonadherence and negative clinical outcomes. Previous studies suggest that impaired insight may arise from brain abnormalities. However, interpretations of these findings are limited due to small sample sizes and inclusion of patients with a narrow range of illness severity and insight deficits.
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