Yashuo Zhao

Abstract Lung cancer remains a major challenge in clinical treatment, as current therapeutic strategies often fail to effectively halt disease progression. Chronic intermittent hypoxia (CIH), a hallmark pathological feature of obstructive sleep apnea (OSA), has been implicated in promoting tumor invasion and metastasis. This study aimed to investigate the potential of hydrogen as an innovative adjunctive therapy for lung cancer.

Abstract Studies have confirmed that elevated glucose levels could lead to renal fibrosis through the process of ferroptosis. Liraglutide, a human glucagon-like peptide-1 (GLP-1) analogue, is a potential treatment option for diabetes. This study aimed to examine the potential of liraglutide (LIRA) in inhibiting ferroptosis and reducing high glucose-induced renal fibrotic injury in mice, and whether the Fsp1-CoQ10-NAD(P)H signal pathway is a mechanism for this effect.

1. Introduction Chronic atrophic gastritis (CAG) is a prevalent and challenging chronic digestive disease. As the world’s fifth most common malignant tumor, gastric cancer (GC) is the most frequently occurring malignant tumor of the digestive system [1,2]. The progression from a precancerous state to GC is a protracted process. In 1975, Correa proposed an “inflammatory–cancer transformation” model, which remains widely accepted today.