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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
BpForms and BcForms : a toolkit for concretely describing non-canonical polymers and complexes to facilitate global biochemical networks
Paul F. Lang1,2,3 na1, Yassmine Chebaro1,2,4, Xiaoyue Zheng1,2, John A. P. Sekar1,2, Bilal Shaikh1,2, Darren A. Natale5 & Jonathan R. Karr1,2 Genome Biology volume 21, Article number: 117 (2020) Cite this article Abstract Non-canonical residues, caps, crosslinks, and nicks are important to many functions of DNAs, RNAs, proteins, and complexes. However, we do not fully understand how networks of such non-canonical macromolecules generate behavior.
Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptorγ
The hRAR? LBD crystallized in presence of the neutral detergent n-dodecyl-?-d-maltopyranoside (C12m) that occupies the coactivator binding cleft of the receptor [ 54 ]. The S371 phosphorylation site of RAR? lies in the surface-exposed loop L9-10, which is easily accessible to cellular protein kinases. To investigate the consequences of S371 phosphorylation, we crystallized a hRAR?
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