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Yasuyuki Matsuda

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Articles

Activation of inflammasomes and mechanisms for intracellular recognition of Listeria monocytogenes

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By Yasuyuki Matsuda, Hajime Yamauchi, Hideki Hara
| Wiley Online Library Verified
Unknown activators for NLRP1b and NLRC5 In addition to the inflammasomes mentioned above, it has been reported that Listeria monocytogenes activates NLRP1b inflammasome by causing metabolic stress.109 Activation of NLRP1b by Listeria depends on the expression of LLO that contributes to the stress by reducing cytosolic ATP levels.
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Plasminogen Tochigi mice exhibit phenotypes similar to wild-type mice under experimental thrombotic conditions

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By Yuko Tashima, Fumiaki Banno, Toshiyuki Kita, Yasuyuki Matsuda
| PLOS
Plasminogen (Plg) is a precursor of plasmin that degrades fibrin. A race-specific A620T mutation in Plg, also known as Plg-Tochigi, originally identified in a patient with recurrent venous thromboembolism, causes dysplasminogenemia with reduced plasmin activity. The Plg-A620T mutation is present in 3–4% of individuals in East Asian populations, and as many as 50,000 Japanese are estimated to be homozygous for the mutant 620T allele.
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