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Articles by Yating Chen
Bindarit ameliorates doxorubicin-induced ovarian damage by suppressing CCL8-dependent macrophage infiltration and NF-κB-mediated inflammation
Abstract Doxorubicin (DOX)-induced ovarian toxicity is a major cause of chemotherapy-related infertility in young female cancer patients, yet the underlying inflammatory mechanisms remain incompletely understood. In this study, we investigated whether CCL8-associated inflammatory remodeling contributes to DOX-induced ovarian injury and evaluated the therapeutic potential of localized chemokine inhibition using Bindarit. A murine model of DOX-induced ovarian injury was established.
Dual attitudes toward doctors: the role of shared decision-making and empathy in frustrated medical treatment in a randomized trial
Abstract Objectives: Patient attitudes have a direct impact on treatment adherence, health status, and satisfaction. This study is to investigate whether increasing physician empathy and patient involvement can improve patient attitudes in the context of frustration. Methods: The study used a three-factor between-subjects design.
Dose optimization of remimazolam as an adjunct to propofol for gastroscopy sedation: a randomized double-blind trial
Abstract Introduction: Propofol-based sedation for gastroscopy is effective but may cause dose-dependent cardiorespiratory depression; therefore, optimizing adjunct strategies to reduce propofol exposure is clinically important. Methods: We conducted a prospective, single-center, randomized, double-blind, dose-response trial to evaluate the propofol-sparing effect of remimazolam during procedural sedation for gastroscopy.
Jasmonate Modulates Strawberry Susceptibility to Anthracnose by Activating SnRK2.1 to Regulate the WRKY50‐JAZ5 Module
1 Introduction Anthracnose, caused by Colletotrichum spp., is one of the most destructive fungal diseases in agriculture, affecting over 760 plant species, including staple crops like maize, rice and soybean, as well as high-value crops such as tea, coffee, tomato, chilli, mango and strawberry (Talhinhas and Baroncelli 2023). Anthracnose typically causes strawberry yield losses of 20%–40% under moderate conditions (Xie et al. 2010; Chung et al.
Single-cell sequencing reveals cellular heterogeneity and molecular mechanisms in tendon and enthesis injury repair
1 Background Tendons are dense fibrous tissues connecting muscles to bones and play a critical role in the musculoskeletal system by resisting tensile forces and bearing mechanical loads. Each tendon attaches at one end to skeletal muscle and at the other to bone, creating a transitional zone between hard and soft tissues. This zone, known as the enthesis, features a gradual transition in tissue organization (Zhou H. et al., 2025).
An Exploratory Study on the Regulatory Effect of Autonomous Sensory Meridian Response on Anxiety: Evidence From Functional Near‐Infrared Brain Imaging Technology
ASMR autonomous sensory meridian response DLPFC dorsolateral prefrontal cortex DMN default mode network fMRI functional magnetic resonance imaging fNIRS functional near-infrared spectroscopy HR hemodynamic responses MFG middle frontal gyrus PFC prefrontal cortex 1 Introduction Anxiety—an organic response that triggers worry and heightens alertness in the face of uncertainty, danger, or potential threats to well-being—profoundly impacts individuals' lives (Huang and Ren 2013).
Nitrogen-Doped Graphene Encapsulating Fe2N for Enhanced Electrocatalytic Conversion of Nitrate to Ammonia
Nitrogen-Doped Graphene Encapsulating Fe2N for Enhanced Electrocatalytic Conversion of Nitrate to Ammonia This study reports the synthesis of a nitrogen-doped graphene encapsulating iron nitride (Fe2N@NC) electrocatalyst with outstanding activity for NO3RR, achieving excellent Faradaic efficiency (FE) for NH3 of 96.11% and high NH3 yield rate of 618.35 mmol hâ1 gcat-1 at -0.5 V versus the reversible hydrogen electrode (RHE).
The effect of disulfidptosis induced by glucose starvation in SLC7A11high ovarian cancer cells
Introduction Ovarian cancer (OC) is the leading cause of death among gynecological cancers, primarily due to the absence of effective early screening and diagnosis methods, resulting in late-stage presentation, high recurrence rates, and significant challenges in diagnosis and treatment. Globally, ovarian cancer ranks eighth in incidence among women, accounting for approximately 3.7% of new cancer cases and 4.7% of cancer deaths in 2020 (Sung et al., 2021).
Characteristics of Phages and Their Interactions With Hosts in Anaerobic Reactors
Conflicts of Interest The authors declare no conflicts of interest. Supporting Information Filename Description emi70040-sup-0001-Supinfo.docxWord 2007 document , 1.4 MB Figure S1. A gene-sharing network of phages from AD reactors and the NCBI Viral RefSeq database. In this network, nodes represent phages, while edges represent similarities. Figure S2.
A novel poly(amidoamine)-modified electrolyte-insulator-semiconductor-based biosensor for label-free detection of ATP
A novel poly(amidoamine)-modified electrolyte-insulator-semiconductor-based biosensor for label-free detection of ATP Adenosine triphosphate (ATP) is crucial for cellular activity. The need for ATP detection in the field of biomedicine is on the rapid rise. Several biosensor-based approaches have been developed as a result of the growing demand for ATP detection.
Biomarcadores proteómicos para la predicción no invasiva de trombos en la orejuela izquierda de pacientes con fibrilación auricular
Ayuda Buscar en la ayuda Buscar en la ayuda Biomarcadores proteómicos para la predicción no invasiva de trombos en la orejuela izquierda de pacientes con fibrilación auricular ZhongHui Xie [1] ; Tao Chen [2] ; Xu Lu [3] ; MaoXiang Zhao [2] ; Yating Chen [2] ; XinYan Wang [2] ; Hang Zhou [2] ; Juan Shen [2] ; Jun Guo [2] ; Yang Li [2] [1] Senior Department of Cardiology, The Sixth Medical Center of PLA General Hospital, Beijing, China; Department of Cardiology, Tianjin Medical University...
Functional Organic Electrochemical Transistor-Based Biosensors for Biomedical Applications
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An activatable red emitting fluorescent probe for monitoring vicinal dithiol proteins fluctuations in stroke model
An activatable red emitting fluorescent probe for monitoring vicinal dithiol proteins fluctuations in stroke model Vicinal dithiol proteins (VDPs) facilitate cellular redox homeostasis and modulate protein synthesis and post-translational modifications through the dynamic equilibrium of dithiol and disulfide bonds.
Evaluating ICESat-2 and GEDI with Integrated Landsat-8 and PALSAR-2 for Mapping Tropical Forest Canopy Height
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Overexpression of OsRbohH Enhances Heat and Drought Tolerance through ROS Homeostasis and ABA Mediated Pathways in Rice (Oryza sativa L.)
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Comparative Study on Phytoplankton Treatment Effectiveness of the Ballast Water Management System with Four Different Processes
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
OsEIN2‐OsEIL1/2 pathway negatively regulates chilling tolerance by attenuating OsICE1 function in rice
CONFLICT OF INTEREST STATEMENT The authors declare no conflict of interest. Supporting Information Filename Description pce14900-sup-0001-Fig_S1.tif3.3 MB Figure S1 The phenotypes of OsEIN2-OE, osein2, OsEIL1-OE, oseil1, OsEIL2-OE, OsEIL2-Ri and Nip under natural chilling conditions. (a) The outdoor temperature and relative humidity during chilling treatment.
The Mediating Role of Psychological Balance on the Effects of Dietary Behavior on Cognitive Impairment in Chinese Elderly
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2D Carbon Nitride-based Electrochemical Aptasensor with Reverse Amplification for Highly-Sensitive Detection of Okadaic Acid in Shellfish
2D Carbon Nitride-based Electrochemical Aptasensor with Reverse Amplification for Highly-Sensitive Detection of Okadaic Acid in Shellfish Okadaic acid (OA) is one of the main virulence factors of diarrheal shellfish toxins (DSP). It is of great significance to detect OA with an accurate, specific and cost-effective technique in the fields of seafood safety and water quality control.
Zero- to One-Dimensional Zn24 Supraclusters: Synthesis, Structures and Detection Wavelength
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Tracking lake drainage events and drained lake basin vegetation dynamics across the Arctic - Nature Communications
Abstract Widespread lake drainage can lead to large-scale drying in Arctic lake-rich areas, affecting hydrology, ecosystems and permafrost carbon dynamics. To date, the spatio-temporal distribution, driving factors, and post-drainage dynamics of lake drainage events across the Arctic remain unclear.
Application value of cardiometabolic index
Donghao Wang,1,* Yating Chen,1,* Yutong Ding,1,* Yongkang Tang,1,* Xiaofen Su,1,* Shiwei Li,1 Haojie Zhang,1,2 Yanyan Zhou,1 Zhiyang Zhuang,1 Qiming Gan,1 Jingcun Wang,1 Yuting Zhang,1 Dongxing Zhao,1 Nuofu Zhang1 1State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, National Center for Respiratory Medicine, Sleep Medicine Center, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical...
Dual-aptamer-based colorimetric assay for the accurate identification of circulating tumor cells via Fe3O4@Pt NP nanozymes and G-quadruplex/hemin for signal amplification
Dual-aptamer-based colorimetric assay for the accurate identification of circulating tumor cells via Fe3O4@Pt NP nanozymes and G-quadruplex/hemin for signal amplification on dual-aptamer recognition and core (Fe3O4)−shell (Pt) nanoparticle (Fe3O4@Pt NP) nanozymes coupled with a G-quadruplex as a signal transducer/amplifier. The results show that the linear range of the designed colorimetric sensor is 50 ~ 4000 cells and the detection limit is 4 cells.
Effects of Thermokarst Lake Drainage on Localized Vegetation Greening in the Yamal-Gydan Tundra Ecoregion
1. Introduction In the context of ongoing global climate change, the Arctic region has emerged as a critical focal point for understanding the intricate interactions between climate dynamics and ecosystem responses [1,2]. One notable phenomenon within this context is the contrasting “browning” and “greening” of the Arctic landscape [3,4,5]. The Arctic tundra biome covers a vast circumpolar area across the northern high latitudes.
Monitoring Thermokarst Lake Drainage Dynamics in Northeast Siberian Coastal Tundra
1. Introduction The polar amplification effect has rendered the cryosphere elements exceptionally susceptible to climate change, making them pivotal indicators of global warming [1]. Over the past few decades, long-term observational data have revealed that the circum-Arctic permafrost region has been undergoing accelerated and profound warming [2], consequently instigating permafrost degradation. The degradation of permafrost typically follows a gradual, top-down process.
Analysis of airway thickening and serum cytokines
Back to Journals » International Journal of Chronic Obstructive Pulmonary Disease » Volume 18 Authors Lin Y, Sang L, Wang J, Chen Y, Lai J, Zhu X, Yang Y, Zhang Z, Liu Y, Wen S, Zhang N , Zhao D Received 14 July 2023 Accepted for publication 25 October 2023 Published 30 October 2023 Volume 2023:18 Pages 2353—2364 DOI https://doi.org/10.2147/COPD.S430650 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Dr Jill Ohar Yiqi...
Socio-Demographic Factors Associated with Rural Residents’ Dietary Diversity and Dietary Pattern: A Cross-Sectional Study in Pingnan, China
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Spatiotemporal Variation in Saline Soil Properties in the Seasonal Frozen Area of Northeast China: A Case Study in Western Jilin Province
Open AccessArticle by Jiejie Shen 1, Yating Chen 1, Qing Wang 1,* and Huicheng Fu 2 1 College of Construction Engineering, Jilin University, Changchun 130026, China 2 Water Conservancy and Hydropower Survey and Design Institute of Jilin Province, Changchun 130021, China * Author to whom correspondence should be addressed.
Application of Nanozymes in Environmental Monitoring, Management, and Protection
Abstract : Nanozymes are nanomaterials with enzyme-like activity, possessing the unique properties of nanomaterials and natural enzyme-like catalytic functions. Nanozymes are catalytically active, stable, tunable, recyclable, and versatile. Therefore, increasing attention has been paid in the fields of environmental science and life sciences. In this review, we focused on the most recent applications of nanozymes for environmental monitoring, environmental management, and environmental protection.
Animals | Free Full-Text | Development of a Multiplex Crystal Digital RT-PCR for Differential Detection of Classical, Highly Pathogenic and NADC30-like Porcine Reproductive and Respiratory Syndrome Virus
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Feng Long 1,†, Yating Chen 2,†, Kaichuang Shi 1,2,*, Yanwen Yin 1, Shuping Feng 1 and Hongbin Si 2,* 1 Guangxi Center for Animal Disease Control and Prevention, Nanning 530001, China 2 College of Animal Science and Technology, Guangxi University, Nanning 530005, China * Authors to whom correspondence should be addressed. † These authors contributed equally to this work.
Charging Stations Selection Using a Graph Convolutional Network from Geographic Grid
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Secure transmission of W-band millimeter-wave based on CNN and dynamic resource allocation
Abstract A secure transmission scheme of a W-band millimeter-wave radio-over-fiber (RoF) system based on cellular neural network (CNN) and dynamic resource allocation is proposed, in which 7-D CNN chaotic system is composed to heighten the anti-deciphering ability of a secure system, and the spectrum resources are optimized by dynamic allocation. The analyses show that the key space of our scheme can reach approximately ${{10}^{112}}$.
Correction for Kincaid et al., “Noncanonical MicroRNA (miRNA) Biogenesis Gives Rise to Retroviral Mimics of Lymphoproliferative and Immunosuppressive Host miRNAs”
Author Correction Rodney P. Kincaid, Yating Chen, Jennifer E. Cox, Axel Rethwilm, Christopher S. Sullivan DOI: 10.1128/mBio.01413-20 AUTHOR CORRECTION Volume 5, no. 2, e00074-14, 2014, https://doi.org/10.1128/mBio.00074-14. R. P. Kincaid, Y. Chen, and C. S. Sullivan would like to note the following. In follow-up confirmatory studies, we have attempted to repeat the work presented in Fig. 5B. We are unable to locate the original cell line reagents used in this work.
Mitigation of Arctic permafrost carbon loss through stratospheric aerosol geoengineering
Abstract The Arctic is warming far faster than the global average, threatening the release of large amounts of carbon presently stored in frozen permafrost soils. Increasing Earth’s albedo by the injection of sulfate aerosols into the stratosphere has been proposed as a way of offsetting some of the adverse effects of climate change.
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