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Yauhen Bandaruk on Muck Rack

Yauhen Bandaruk

As seen in: BioRxiv
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Articles

SH3BP2 regulates the organization of the neuromuscular synapses through protein-driven phase separation

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By Bhola S. Pradhan, Anna Siudzinska, Krzysztof Bernadzki, Yauhen Bandaruk
| BioRxiv
Abstract The molecular mechanisms underlying the development and maintenance of the neuromuscular junction are poorly understood, even though the malfunction of these specialized synapses is associated with severe genetic and autoimmune disorders. The identity of factors controlling the maintenance mechanisms of postsynaptic acetylcholine receptors (AChR) in high-density has been elusive and is of great interest to the pharma industry, searching for possible new targets for disease interventions.
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