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Yaying He on Muck Rack

Yaying He

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Articles

Loss of TSPOAP1 exacerbates mitochondrial dysfunction and neuronal apoptosis after intracerebral hemorrhage

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By Yuhao Duan, Chengyang Li, Mi Zhang, Hui Xian Gan, Xuan Zhai, Yaying He
| Nature Verified
Abstract Intracerebral hemorrhage (ICH) induces severe secondary neuronal injury, in which mitochondrial dysfunction and apoptosis play central roles. Accumulating evidence suggests that mitochondrial failure represents a critical convergence point linking diverse injurious stimuli to neuronal apoptosis after ICH. However, the molecular mechanisms that connect mitochondrial dysfunction to irreversible apoptotic commitment remain incompletely understood.
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