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Yaying Zeng on Muck Rack

Yaying Zeng

As seen in: Frontiers, Canadian Journal of Infectious Diseases & Medical Microbiology
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Articles

Direct neuronal reprogramming for neurological diseases: applications, translational Challenges, and future directions

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By Yu Chen, Zhe Zheng, Peiqi Zhao, Jiajie Zhu, Haoliang Zhu, Yaying Zeng, Anke Zhang, Yuanbo Pan, Kankai Wang, Hangzhe Sun, Bowen Shang
| Frontiers
Abstract Neurological diseases, often caused by irreversible loss of terminally differentiated neurons, present considerable challenges to treatment due to the limited regenerative capacity of these neurons. Although induced pluripotent stem cells hold promise for neuronal regeneration, their clinical application is constrained by risks, including tumorigenicity, incomplete neuronal maturation, and immune rejection.
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