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Articles

TAK1 operates at the primary cilium in non-canonical TGFB/BMP signaling to control heart development

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By Canan Doganli, Daniel Baird, Yeasmeen Ali, Oskar Kaaber Thomsen
| biorxiv.org
Abstract Transforming Growth Factor-Beta-Activated Kinase 1 (TAK1/MAP3K7), along with its upstream regulators TAK1-Binding Protein 2 (TAB2) and the catalytic alpha-subunit of Protein Kinase A (PKA-Cα/PRKACA), has been identified as a pivotal player in regulation of developmental processes.
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