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Yemiao Chen

As seen in: Frontiers in Public Health
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Articles

Evidence-based standardization of infectious disease biobanking: aligning specimen preservation and clinical metadata with in vitro diagnostic clinical trials requirements

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By Chao Xia, Fang Cheng, Miaomiao Qi, Jing Ouyang, Bangyan Guan, Xingjian Liao, Yemiao Chen
| Frontiers in Public Health Verified
Abstract Background: Biobanks accelerate in vitro diagnostic (IVD) clinical trials by providing annotated, quality-controlled biospecimens. However, a persistent translational gap remains because the specific requirements of IVD trials—including sample matrices, preservation protocols, aliquot volumes, freeze–thaw tolerability, and clinical metadata—have not been systematically characterized.
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