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Yi Chun Lai on Muck Rack

Yi Chun Lai

As seen in: ACS Publications, MDedge Dermatology
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Articles

Molecular Engineering of Stimuli-Activatable Protein Degraders for Precise Cancer Therapy Click to copy article link Article link copied!

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By Jing Gao, Yi Chun Lai, Bo Hou
| ACS Publications
Abstract Click to copy section linkSection link copied! Conspectus The emerging advance of targeted protein degradation (TPD) technology offers a novel option for protein modulation, ensuring a more durable and precise therapeutic impact for cancer management. While promising, complete degradation of the proteins of interest (POIs) in both pathological and normal tissues may cause severe side effects.
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Rational Design of Antimony-Based Zintl Clusters: Unveiling Unconventional Bonding and Architectures

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By Yi Chun Lai, Wei-Xing Chen, Wen-Juan Tian, Alvaro Muñoz-Castro
| ACS Publications
Abstract Click to copy section linkSection link copied! Conspectus The past decade has witnessed rapid growth in the synthesis of main-group element clusters, driven by advances in the design of Zintl phase precursors and their integration with organometallic reagents. These strategies have unlocked unprecedented structural motifs and bonding patterns, greatly enriching the landscape of main-group cluster chemistry.
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Lichen Planus and Lichenoid Drug Eruption After Vaccination

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By Yi Chun Lai, Yik Weng Yew
| MDedge Dermatology Verified
Lichen planus (LP) is a chronic inflammatory dermatosis of unknown origin that involves the skin and mucous membranes, and lichenoid drug eruption (LDE) is an uncommon cutaneous adverse reaction to a medication.1 The manifestations resemble each other clinically, and sometimes it is difficult to differentiate between them on histology. The pathogenesis still is not well characterized, especially the key initiating event that leads to the development of LP or LDE postimmunization.
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